Methods for heat-stabilizing proteins with specific binding activities
US7750117B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Feb 11, 2004 |
| Grant date | Jul 6, 2010 |
| Priority date | — |
| Expiry date | Apr 11, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/40
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
It is disclosed here that a protein with a heat-labile specific binding activity can be stabilized with a saccharide compound with regard to the binding activity. To heat-stabilize the protein, it is mixed with a saccharide compound in a liquid suspension and the suspension is then dried to produce a solid that contains the protein and the saccharide. The saccharide compounds that possess the protein heat-stabilization activity include monosaccharides, disaccharides, polysaccharides, alkylated monosaccharides, alkylated disaccharides, alkylated polysaccharides, monosaccharide alcohols and alkylated monosaccharide alcohols.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.