Compositions and methods of use of ORF 554 from beta hemolytic streptococcal strains
US7754226B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Jun 19, 2009 |
| Grant date | Jul 13, 2010 |
| Priority date | — |
| Expiry date | Jun 19, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/975
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compositions and methods of use comprising peptidyl-prolyl isomerase (PPI) polypeptides of group C and G streptococci and polynucleotides encoding same. The invention also relates to immunogenic compositions comprising the PPI polypeptides and polynucleotides, as well as antibodies and antibody fragments that bind the PPI polypeptides. In addition, the invention relates to methods of inducing an immune response in a subject against beta hemolytic streptococci using the immunogenic compositions, as well as conferring passive immunity by administering a therapeutic antibody or antibody fragment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.