Patent · US Active

Stabilized FGF formulations containing reducing agents

US7754686B2 · kind B2 · utility

2Cited by

14References

13Claims

0Family size

Assignee

Novartis Vaccines and Diagnostics, Inc. · US

Inventors

Robert V. Hageman · Boulder, US
Bret A. Shirley · Concord, US
Kamaljit Bajwa · Danville, US

Key dates

Filing date	Aug 31, 2001
Grant date	Jul 13, 2010
Priority date	—
Expiry date	Nov 11, 2028

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K47/26
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Stabilized FGF compositions are provided. The compositions comprise FGF or variant thereof and at least one reducing agent in an amount sufficient to inhibit FGF oxidation. Methods for increasing stability of FGF or variant thereof in a liquid or lyophilized composition and for increasing storage stability of such a composition are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.