Bioactive peptide-based probes
US7759468B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 5, 2004 |
| Grant date | Jul 20, 2010 |
| Priority date | — |
| Expiry date | May 28, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/531
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for preparing a site-specific peptide probe, wherein the peptide is specific to a receptor, includes modifying a marker to include a tether molecule and covalently binding the tether molecule to the peptide. The present invention also provides a labeled probe, comprising a peptide specific for a receptor and a marker. The marker is modified to include a tether molecule capable of covalently binding to the peptide. The peptide is typically derived from a bacteriophage or is a synthetic analog or derivative of the peptide. The receptor will typically be found on a surface of a bacterial cell. The method and probe of the invention are suitable for a rapid assay for a bacteria in a complex mixture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.