Patent · US Active

Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste

US7763431B1 · kind B1 · utility

38Cited by

4References

93Claims

0Family size

Assignee

SENOMYX, INC. · US

Inventors

Mark Zoller · San Diego, US
Xiaodong Li · Bellevue, US
Lena Staszewski · San Diego, US
Shawn O'Connell · Encinitas, US
Sergey Zozulya · San Diego, US
Jon Elliot Adler · San Diego, US
Hong Xu · San Diego, US
Fernando Echeverri · Chula Vista, US

Key dates

Filing date	Dec 2, 2003
Grant date	Jul 27, 2010
Priority date	—
Expiry date	Jan 8, 2027

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/726
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Binding assays for identifying compounds that induce or modulate the T1R2/T1R3 (sweet) receptor associated taste are provided. These binding assays detect the specific binding or a component to a T1R2/T1R3 (sweet) taste receptor or detect modulation (inhibition or enhancement) of the binding of another compound, e.g., saccharin or another sweetener to a T1R2/T1R3 (sweet) taste receptor. Compounds that are identified in these binding assays have potential application of T1R2/T1R3 sweet taste receptor modulators and can be used as flavor additives in compositions for human or animal consumption.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.