Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis

US7763643B2 · kind B2 · utility

Assignee

• Sanofi-Aventis Deutschland GMBH · DE

Inventors

• Hans-Jochen Lang · Hofheim, DE
• Uwe Heinelt · Wiesbaden, DE
• Armin Hofmeister · Frankfurt, DE
• Klaus Wirth · Frankfurt am Main, DE
• Michael Gekle · Coburg, DE
• Markus Bleich · Brechen, DE

Key dates

• Filing date: Jan 30, 2009
• Grant date: Jul 27, 2010
• Expiry date: Jan 30, 2029

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention comprises compounds and compositions comprising substituted thiophene derivatives with the following backbone structure:The compounds of this type are of useful in the treatment of various disorders, such as, respiratory disorders and snoring, acute and chronic disorders, disorders induced by ischemic and/or reperfusion events and by proliferative or fibrotic events, disorders of the central nervous system and lipid metabolism, diabetes, blood coagulation and infection by parasites.