Intermediates for the preparation of lipoxin A4 analogs

US7763743B2 · kind B2 · utility

Assignee

• Bayer Schering Pharma AG · DE

Inventors

• Danja Grossbach · Wuppertal, DE
• William Guilford · San Leandro, US
• Michael Sander · Blankenloch, DE

Key dates

• Filing date: Nov 3, 2006
• Grant date: Jul 27, 2010
• Expiry date: Jun 1, 2027

Classification

• Technology area (CPC —): General

Abstract

This invention is directed to compounds useful as intermediates in the synthesis of lipoxin A4 analogs of the following formulas (I) and (II):wherein R1, R2, R3, R4 and R5 are described herein. These analogs are useful in treating inflammatory and autoimmune disorders in humans. These analogs are also useful in treating pulmonary or respiratory tract inflammation in humans.