Method for determining coagulation activation and device for carrying out said method
US7767458B2 · kind B2 · utility
1Cited by
10References
8Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 22, 2006 |
| Grant date | Aug 3, 2010 |
| Priority date | — |
| Expiry date | Feb 22, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/86
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method is disclosed of assaying circulating microparticles contained in a sample of whole blood or blood plasma from a patient to determine the patient's ability to generate thrombin or Factor Xa as blood-clotting factors, wherein the circulating microparticles are microparticles of platelets, endothelial cells, monocytes, and smooth muscle cells, which carry on their surfaces both negatively charged phospholipids as well as tissue factor. The results of the assay may be used to determine the ability of the patient to generate thrombin or Factor Xa as blood clotting factor based upon the circulating microparticles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.