Fluorescence detection enhancement using photonic crystal extraction
US7768640B2 · kind B2 · utility
33Cited by
21References
42Claims
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Key dates
| Filing date | Nov 19, 2007 |
| Grant date | Aug 3, 2010 |
| Priority date | — |
| Expiry date | Aug 30, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG02B2006/1213
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Enhancement of fluorescence emission from fluorophores bound to a sample and present on the surface of two-dimensional photonic crystals is described. The enhancement of fluorescence is achieved by the combination of high intensity near-fields and strong coherent scattering effects, attributed to leaky photonic crystal eigenmodes (resonance modes). The photonic crystal simultaneously exhibits resonance modes which overlap both the absorption and emission wavelengths of the fluorophore. A significant enhancement in fluorescence intensity from the fluorophores on the photonic crystal surface is demonstrated.
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