Patent · US Active

BIR domain binding compounds

US7772177B2 · kind B2 · utility

4Cited by
9References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 16, 2006
Grant dateAug 10, 2010
Priority date
Expiry dateJul 28, 2027

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K5/06069
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention is directed towards an isomer, an enantiomer, a diastereoisomer, or a tautomer of a pyrrolidine compound represented by Formula I:in which the substituents R1, R1a, R2, R2a, R3, A and Q are defined herein; or a prodrug, or a salt thereof, and which bind to IAP BIR domains. In particular, the compounds are useful in treating proliferative disorders such as cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.