Glucopyranosyl-substituted ((hetero)arylethynyl-benzyl)-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture

US7772378B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Frank Himmelsbach · Mittelbiberach, DE
• Matthias Eckhardt · Hannover, DE
• Peter Eickelmann · Mittelbiberach, DE
• Leo Thomas · Biberach, DE
• Edward Barsoumian · Toyonaka, JP

Key dates

• Filing date: Feb 22, 2006
• Grant date: Aug 10, 2010
• Expiry date: Feb 16, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Glucopyranosyl-substituted (hetero)arylethynyl-benzene derivatives of the general formula Iwhere the groups R1 to R6 as well as R7a, R7b, R7c are defined according to claim 1, including the tautomers, the stereoisomers thereof, the mixtures thereof and the salts thereof. The compounds according to the invention are suitable for the treatment of metabolic disorders.