Patent · US Active

Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells

US7772408B1 · kind B1 · utility

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0References

14Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Julia Vennekamp · Kiel, DE
Heike Wulff · Davis, US
K. George Chandy · Laguna Beach, US
Stephan Grissmer · Irvine, US
Wolfram Hansel · Kronshagen, DE

Key dates

Filing date	Aug 29, 2003
Grant date	Aug 10, 2010
Priority date	—
Expiry date	Jul 16, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D493/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Compositions of matter comprising 5-phenylalkoxypsoralen compounds and their method of synthesis and use. The compounds are useable to treat diseases or disorders in human or veterinary patients, including autoimmune diseases such as multiple sclerosis. The compounds inhibit potassium channels, including the Kv1.3 channel and at least some of the therapeutic effects of such compounds may be due at least in part to potassium channel inhibition.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.