“Droplet pickup ion source” coupled to mobility analyzer apparatus and method
US7772548B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | May 12, 2008 |
| Grant date | Aug 10, 2010 |
| Priority date | — |
| Expiry date | Apr 15, 2029 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/145
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An ion mobility analyzer includes at least one of a “differential mobility analyzer”, an “ion mobility spectrometer” and a “differential mobility spectrometer”, to which charged molecules of interest are fed. Ions are fed to the ion mobility analyzer from a “droplet pickup ion source” including an electrospray ion source at a capillary end, from which charged droplets formed from a solvent mixture having substantially none of the molecules of interest emerge. The charged droplets are pulled by an electric field into a “pickup region” filled with a buffer gas at a pressure or a region close to the surface of a sample, where the charged droplets incorporate the molecules of interest and transfer the charge of the charged droplets to the molecules of interest, when the liquid in the charged droplets has evaporated in a heated desolvation region that is separate or integral with respect to the “pickup region”.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.