Microdevice containing photorecognizable coding patterns and methods of using and producing the same

US7776543B2 · kind B2 · utility

Assignees

• AVIVA BIOSCIENCES CORPORATION · US
• TSINGHUA UNIVERSITY · CN
• CAPTIALBIO Corporation · CN

Inventors

• Lei Wu · San Diego, US
• Xiaobo Wang · San Diego, US
• Guoliang Tao · San Diego, US
• Junquan Xu · Fujian, CN
• Jing Cheng · Beijing, CN
• Mingxiang Huang · San Diego, US
• Baoquan Sun · Damaishan, CN
• Wei Shao · Frederick, US
• Litian Liu · Beijing, CN
• Depu Chen · Beijing, CN
• David M. Rothwarf · Village of La Jolla, US
• Weiping Yang · San Diego, US

Key dates

• Filing date: Aug 7, 2001
• Grant date: Aug 17, 2010
• Expiry date: Mar 4, 2022

Classification

• Technology area (CPC —): General

Abstract

This invention relates generally to the field of moiety or molecule analysis, isolation, detection and manipulation and library synthesis. In particular, the invention provides a microdevice, which microdevice comprises: a) a substrate; and b) a photorecognizable coding pattern on the substrate. Preferably, the microdevice does not comprise an anodized metal surface layer. Methods and kits for isolating, detecting and manipulating moieties, and synthesizing libraries using the microdevices are also provided. The invention further provides two-dimensional optical encoders and uses thereof.