Mammalian IAP gene family, primers, probes and detection methods
US7776552B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Aug 3, 2006 |
| Grant date | Aug 17, 2010 |
| Priority date | — |
| Expiry date | Aug 3, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2510/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and primer and probes for the identification and isolation of additional IAP genes. In addition, methods for treating diseases and disorders involving apoptosis are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.