Use of neuropeptides for ligament healing
US7776815B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 23, 2005 |
| Grant date | Aug 17, 2010 |
| Priority date | — |
| Expiry date | May 25, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/2278
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are a method and a corresponding pharmaceutical composition for treating damaged ligaments. Neurogenic compounds in general and neuropeptides in particular have been found to be highly effective in stimulated repair of ligaments damaged due to traumatic injury, ligament disease, and disuse. Preferred active ingredients for use in the method and corresponding pharmaceutical composition include calcitonin gene-related peptide (CGRP), cholecystokinin (CCK), dynorphin, enkephalin, galanin, neuropeptide Y (NPY), neurotensin, somatostatin, substance P (SP), thyrotropin-releasing hormone (TRH), vasoactive intestinal peptide (VIP).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.