Pharmaceutical compounds
US7776856B2 · kind B2 · utility
14Cited by
12References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 25, 2005 |
| Grant date | Aug 17, 2010 |
| Priority date | — |
| Expiry date | Apr 10, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Fused pyrimidines of formula (I):where A is a thiophene or furan ring and R1-R3 and n are defined in the specification. These compounds have activity as inhibitors of PI3K and may thus be used to treat diseased and disorders arising from abnormal cell growth, function or behavior associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine disorders and neurological disorders. Processes for synthesizing the compounds are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.