Fused bicyclic pyrimidines

US7776864B2 · kind B2 · utility

Assignee

• Bayer Schering Pharma AG · DE

Inventors

• Swen Hölder · London, GB
• Matthias Vennemann · Konstanz, DE
• Gerrit Beneke · Allensbach, DE
• Armin Zülch · Schriesheim, DE
• Volker Gekeler · Konstanz, DE
• Thomas Beckers · Konstanz, DE
• Astrid Zimmermann · Konstanz, DE
• Hemant Joshi · Navi Mumbai, IN

Key dates

• Filing date: Aug 14, 2008
• Grant date: Aug 17, 2010
• Expiry date: Aug 14, 2028

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula (I)a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.