Compositions and methods for inhibiting growth and metastasis of melanoma
US7776894B2 · kind B2 · utility
16Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 15, 2008 |
| Grant date | Aug 17, 2010 |
| Priority date | — |
| Expiry date | Aug 15, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/52
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There are provided methods of inhibiting growth and metastasis of melanoma, methods of sensitizing melanoma cells to apoptosis, and methods of treating a subject having melanoma using acetyl isogambogic acid, celastrol, or a derivative thereof. There are further provided derivatives of celastrol and compositions comprising acetyl isogambogic acid, celastrol, or a derivative thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.