Patent · US Active

5-cyano-prostacyclin derivatives as agents for the treatment of influenza a viral infection

US7776896B2 · kind B2 · utility

1Cited by

5References

10Claims

0Family size

Assignee

Bayer Schering Pharma AG · DE

Inventors

William Guilford · San Leandro, US
Werner Skuballa · Berlin, DE
Daryl Faulds · Mill Valley, US
Monica J. Kochanny · San Rafael, US
Wheeseong Lee · Orinda, US
Bernd Raduchel · Berlin, DE

Key dates

Filing date	Mar 27, 2008
Grant date	Aug 17, 2010
Priority date	—
Expiry date	Mar 27, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D405/06
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

This invention is directed to compounds of formula (I):where A, B, D, E, m, and R1-R5 are as described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, clathrates, or prodrugs thereof, which compounds are useful in treating respiratory diseases associated with influenza A viruses, such as for example H5N1 and its mutations. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.