Neurotransmitter sensors and methods of using the same
US7777016B2 · kind B2 · utility
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8References
18Claims
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Key dates
| Filing date | Oct 14, 2005 |
| Grant date | Aug 17, 2010 |
| Priority date | — |
| Expiry date | Nov 8, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Neurotransmitter biosensors are disclosed, including YbeJ-based glutamate binding biosensors, comprising a neurotransmitter binding domain conjugated to donor and fluorescent moieties that permit detection and measurement of Fluorescence Resonance Energy Transfer upon binding neurotransmitter. Such biosensors are useful for the detection of neurotransmitter concentrations in vivo and in culture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.