Transformed bryophyte cell having disrupted endogenous alpha 1,3-fucosyl and beta 1,2-xylosyl transferase encoding nucleotide sequences for the production of heterologous glycosylated proteins

US7781197B2 · kind B2 · utility

Assignee

• GREENOVATION BIOTECH GMBH · DE

Inventors

• Ralf Reski · Kirchzarten, DE
• Gilbert Gorr · Glückstadt, DE
• Eva Decker · Glückstadt, DE
• Christian Stemmer · Glückstadt, DE
• Otmar Lienhart · Glückstadt, DE
• Anna Koprivova · Glückstadt, DE

Key dates

• Filing date: Dec 18, 2003
• Grant date: Aug 24, 2010
• Expiry date: Feb 20, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P21/005
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Bryophyte plants and bryophyte plant cells comprising dysfunctional fucT and xylT genes and an introduced glycosyltransferase gene, methods for the production of glycosylated proteins therewith, vectors and uses thereof.