SEMA3B inhibits tumor growth and induces apoptosis in cancer cells
US7781413B2 · kind B2 · utility
3Cited by
3References
11Claims
0Family size
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Key dates
| Filing date | Oct 31, 2002 |
| Grant date | Aug 24, 2010 |
| Priority date | — |
| Expiry date | Sep 2, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/57484
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention identifies the semaphorin polypeptide SEMA3B as a tumor suppressor. This molecule can inhibit tumor growth and induce apoptosis of tumor cells when produced internally in a cancer cell via gene transfer, or when applied extracellularly. These observations permit new methods for treatment and diagnosis of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.