Process for delivering sirna to cardiac muscle tissue
US7781415B2 · kind B2 · utility
2Cited by
4References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 3, 2004 |
| Grant date | Aug 24, 2010 |
| Priority date | — |
| Expiry date | Apr 20, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/0083
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process for delivering a polynucleotide to a cardiac tissue cell in a mammal is described, comprising introducing a composition consisting of a polynucleotide into a blood vessel and increasing permeability of the blood vessel to the polynucleotide. The polynucleotide can be a small interfering RNA or microRNA and inhibit gene expression in the cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.