Tyrosine derivatives substituted by N-arylacryloyl as agonists of hPPAR alpha and/or hPPAR gamma

US7781468B2 · kind B2 · utility

Assignee

• Beijing Molecule Science and Technology Co., Ltd. · CN

Inventors

• Song Li · Beijing, CN
• Xinbo Zhou · Beijing, CN
• Lili Wang · Beijing, CN
• Cheng Xu · Chengdu, CN
• Chengmai Ruan · Beijing, CN
• Cuifang Lin · Beijing, CN
• Junhai Xiao · Beijing, CN
• Zhibing Zhen · Beijing, CN
• Hongying Liu · Beijing, CN
• Yunde Xie · Beijing, CN
• Zhong Wu · 红钢城街道, CN
• Hao Cui · Beijing, CN

Key dates

• Filing date: Mar 2, 2005
• Grant date: Aug 24, 2010
• Expiry date: Jan 8, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a compound of formula I, racemates, optically active isomers, or pharmaceutically acceptable salts or solvates thereof, and a pharmaceutical composition comprising the compound, the various radicals in the formula I are the same as defined in the claims. The present invention also relates to a process for preparing the compound of formula I and use of said compound in the preparation of a medicament for the treatment of hyperglycemia, dyslipidemia, type II diabetes mellitus including associated diabetic dyslipidemia