Transgenic non-human animals for pharmacological and toxicological studies
US7781643B2 · kind B2 · utility
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11References
14Claims
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Assignee
Inventor
Key dates
| Filing date | Apr 13, 2009 |
| Grant date | Aug 24, 2010 |
| Priority date | — |
| Expiry date | Apr 13, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes or portions of genes have been replaced by homologues from another animal to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.