Conjugates comprising a biodegradable polymer and uses therefor
US7785618B2 · kind B2 · utility
18Cited by
8References
10Claims
0Family size
Inventors
Key dates
| Filing date | Aug 20, 2004 |
| Grant date | Aug 31, 2010 |
| Priority date | — |
| Expiry date | Jan 2, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08L59/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Biologically active agents covalently linked to a polymer. The polymer is preferably a biodegradable polymer are provided. The biologically active agent is preferably a protein, such as an extracellular soluble protein, e.g., an extracellular enzyme. The enzyme can be an apyrase, e.g., NTPDase. Conjugates of the invention can be used as therapeutics in subjects. For example, a conjugate comprising an apyrase can be used for treating and preventing thrombosis, atherosclerotic plaque complications and vascular disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.