Hyperphotosynthetic organisms

US7785861B2 · kind B2 · utility

Assignee

• Joule Unlimited, Inc. · US

Inventors

• Eric Devroe · Pflugerville, US
• Sriram Kosuri · Cambridge, US
• David Arthur Berry · Brookline, US
• Noubar B. Afeyan · Lexington, US
• Frank A. Skraly · Watertown, US
• Dan E. Robertson · San Diego, US
• Brian D. Green · Cambridge, US
• Christian Perry Ridley · Acton, US

Key dates

• Filing date: Nov 10, 2008
• Grant date: Aug 31, 2010
• Expiry date: Jan 31, 2029

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P60/20
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present disclosure identifies pathways and mechanisms to confer improved industrial fitness on engineered organisms. It also discloses engineered organisms having improved industrial fitness. Synthetic biologic engineering modules are disclosed that provide for light capture, carbon dioxide fixation, NADH production, NADPH production, thermotolerance, pH tolerance, flue gas tolerance, salt tolerance, nutrient independence and near infrared absorbance. The disclosed engineered organisms can include one or more of these modules. Also provided are methods of using the engineered organism to produce carbon-based products of interest, biomass or pharmaceutical agents.