Mutein of a bone morphogenetic protein and use thereof

US7786080B2 · kind B2 · utility

Assignee

• Julius-Maximilians-Universitat Wurzburg · DE

Inventors

• Thomas Müller · Biberach, DE
• Walter Sebald · Würzburg, DE

Key dates

• Filing date: Mar 4, 2005
• Grant date: Aug 31, 2010
• Expiry date: Jan 31, 2027

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is related to a mutein of a bone morphogenetic protein, whereby the mutein comprises an amino acid substitution compared to the wildtype of the bone morphogenetic protein at the amino acid position corresponding to amino acid position 51 of human BMP-2.