Patent · US Expired

Drug conjugates of ion channel modulating compounds

US7786119B2 · kind B2 · utility

7Cited by

12References

6Claims

0Family size

Assignee

Cardiome Pharma Corp. · CA

Inventors

Elizabeth L. S. Cheu · Halifax, CA
Lewis Siu Leung Choi · Burnaby, CA
Doug Ta Hung Chou · Vancouver, CA
Allen Davidoff · Calgary, CA
Alan M. Ezrin · Miami, US
Grace Jung · New Westminster, CA
Bertrand M. C. Plouvier · Vancouver, CA
Aregahegn Yifru · Benicia, US

Key dates

Filing date	Mar 31, 2005
Grant date	Aug 31, 2010
Priority date	—
Expiry date	Nov 18, 2025

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/05
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention is directed to drug conjugates of certain ion channel modulating compounds having the following formula:wherein A, X, R1, R2, R3, R4, R5, LB, L and DM are defined herein, including isolated enantiomeric and diastereomeric isomers thereof, and mixtures thereof. Pharmaceutical compositions and methods of use are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.