Patent · US Active

Anti-IP-10 antibodies and methods of use thereof

US7786268B2 · kind B2 · utility

8Cited by
0References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 28, 2008
Grant dateAug 31, 2010
Priority date
Expiry dateOct 12, 2028

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/92
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to fully human antibodies, and fragments thereof, that bind to interferon-inducible-protein-10 (IP-10, CXCL10), thereby modulating the interaction between IP-10 and its receptor, CXCR3, and/or modulating the biological activities of IP-10. The invention also relates to the use of such anti-IP-10 antibodies in the prevention or treatment of immune-related disorders and in the amelioration of one or more symptoms associated with an immune-related disorder.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.