Method and apparatus for conjugate quadrature interferometric detection of an immunoassay
US7787126B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 26, 2008 |
| Grant date | Aug 31, 2010 |
| Priority date | — |
| Expiry date | Jul 14, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/7779
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A detection system for detecting target material is provided. The system comprises a photonic structure having a reflectance-band and associated side bands; an illumination source for illuminating at a wavelength in at least one of an edge of the reflectance-band and the side bands of the photonic structure and for generating a return beam; a detector system having an intensity-sensitive channel configured to detect an in-line signal from the return beam and a phase-sensitive channel configured to detect a differential phase contrast signal from the return beam; and a processing system for receiving and adding in quadrature the in-line signal and the differential phase contrast signal to generate a joint signal, and for determining one of the presence or the absence of the target material on the photonic structure using the joint signal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.