Patent · US Active

Optical arrangement for the production of a light-sheet

US7787179B2 · kind B2 · utility

31Cited by

2References

13Claims

0Family size

Assignee

Carl Zeiss Micromanaging GmbH · DE

Inventors

Helmut Lippert · Jena, DE
Matthias Wald · Jena, DE
Benno Radt · Jena, DE

Key dates

Filing date	Nov 28, 2007
Grant date	Aug 31, 2010
Priority date	—
Expiry date	Jun 16, 2028

Classification

Technology area (CPC G)Physics
CPC primaryG02B26/08
WIPO fieldOptics
WIPO sectorInstruments

Abstract

The invention is directed to an optical arrangement with a light source for emitting a light bundle and with optical elements for transforming this light bundle into the shape of a light sheet, particularly suitable for illuminating individual planes of a three-dimensional specimen in selective plane illumination microscopy (SPIM). According to the invention, means are provided for varying the cross section of the light sheet, for varying the length of the light sheet and/or for influencing the direction in which individual beam components extending within the light sheet are directed to the specimen substance. This makes it possible to adapt the geometry of the light sheet to the illumination requirements for observing one and the same specimen plane with a plurality of different objectives and, if required, to reduce shadows occurring within the observed specimen plane as a result of the illumination.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.