Mapping of proteins along chromatin by chromatin cleavage
US7790379B2 · kind B2 · utility
8Cited by
1References
56Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 19, 2006 |
| Grant date | Sep 7, 2010 |
| Priority date | — |
| Expiry date | Apr 11, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6827
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is directed to a method for localizing, in chromatin or DNA, the binding loci of a chromatin or DNA binding protein comprising the following steps: According to an embodiment of the invention, the regulatable enzyme is a regulatable protease. The mapping step may be carried out on specific DNA fragments, or on a chromosome-wide scale or a genome-wide scale.The present invention is also directed to kits for carrying out the methods of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.