Alanine 2,3-aminomutases and related polynucleotides
US7790432B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 25, 2005 |
| Grant date | Sep 7, 2010 |
| Priority date | — |
| Expiry date | Mar 9, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/90
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is directed to polypeptides that have enhanced alanine 2,3-aminomutase (AAM) activity and/or thermostability relative to the wild-type enzymes that have incidental AAM activity as a result of cross reactivity with alanine. In addition, the present invention is directed to a polynucleotides that encodes for the AAM polypeptides of the present invention, to nucleic acid sequences comprising the polynucleotides, to expression vectors comprising the polynucleotides operatively linked to a promoter, to host cells transformed to express the AAM polypeptides, and to a method for producing the AAM polypeptides of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.