Patent · US Active

Method for production of (1S)-3-chloro-1-(2-thienyl)-propan-1-ol using alcohol dehydrogenase from thermoanaerobacter

US7790436B2 · kind B2 · utility

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2References

4Claims

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Assignee

BASF SE

Inventor

Michael Breuer · Darmstadt, DE

Key dates

Filing date	Dec 13, 2006
Grant date	Sep 7, 2010
Priority date	—
Expiry date	Dec 25, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P41/002
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A process for preparing optically active (1S)-3-chloro-1-(2-thienyl)propan-1-ol of the formula Iby, in a medium comprising 3-chloro-1-(2-thienyl)propan-1-one of the formula IIreducing this compound to the compound of the formula I by means of an alcohol dehydrogenase from the Thermoanaerobacter genus, and isolating the product formed in substantially enantiomerically pure form.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.