Monocyclic and bicyclic compounds and methods of use
US7790726B2 · kind B2 · utility
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Key dates
| Filing date | Aug 14, 2006 |
| Grant date | Sep 7, 2010 |
| Priority date | — |
| Expiry date | Jan 12, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally monocyclic and bicyclic compounds and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.