High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography

US7791734B2 · kind B2 · utility

Assignees

• Lawrence Livermore National Security, LLC · US
• The Regents of the University of California · US

Inventors

• Scot S. Olivier · Livermore, US
• John S. Werner · Fishkill, US
• Robert J. Zawadzki · Sacramento, US
• Sophie Pierrette Laut · La Cañada Flintridge, US
• Steven M. Jones · Dunstable, US

Key dates

• Filing date: May 2, 2006
• Grant date: Sep 7, 2010
• Expiry date: Jun 12, 2026

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B3/102
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

This invention permits retinal images to be acquired at high speed and with unprecedented resolution in three dimensions (4×4×6 μm). The instrument achieves high lateral resolution by using adaptive optics to correct optical aberrations of the human eye in real time. High axial resolution and high speed are made possible by the use of Fourier-domain optical coherence tomography. Using this system, we have demonstrated the ability to image microscopic blood vessels and the cone photoreceptor mosaic.