Method of producing a cationic liposomal preparation comprising a lipophilic compound

US7794747B2 · kind B2 · utility

Assignee

• Medigene Oncology GmbH · DE

Inventors

• Carsten Mundus · Biberach an der Riß, DE
• Christian Welz · Brixlegg, AT
• Oliver Schramel · Ismaning, DE
• Heinrich Haas · Mainz, DE
• Thomas Fichert · Warendorf, DE
• Brita Schulze · Walchensee, DE
• Toralf Peymann · Los Angeles, US
• Uwe Michaelis · Darmstadt, DE
• Michael Teifel · Weiterstadt, DE
• Friedrich Gruber · Krailling, DE
• Gerhard Winter · Dossenheim, DE

Key dates

• Filing date: Dec 22, 2004
• Grant date: Sep 14, 2010
• Expiry date: Jul 23, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method for producing a cationic liposomal preparation comprising a lipophilic active compound with physical and chemical stability during manufacturing, storing and reconstituting, and further a cationic liposomal preparation obtainable by this method as well as specific cationic liposomal preparations as well as pharmaceutical compositions are disclosed.