Use of a nucleic acid/PEI complex
US7795031B2 · kind B2 · utility
6Cited by
4References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 21, 2001 |
| Grant date | Sep 14, 2010 |
| Priority date | — |
| Expiry date | Sep 21, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns the use of a nucleic acid/cationic polymer complex, preferably polyethyleneimine (PEI) for preparing a composition for intraventricular stereotactic screening of stem cells of the brain for preparing a medicine for treating neurodegenerative and/or demyelinating disease. The invention further concerns a method for obtaining an animal whereof the genome of stem cells of the brain are modified by using said complex. The invention also concerns a method for obtaining an animal for screening compounds designed to modify the disposition of stem cells of the brain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.