Methods for treating a neurological disorder by peripheral administration of a transforming growth factor alpha (TGF-a)
US7795202B2 · kind B2 · utility
2Cited by
14References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 10, 2002 |
| Grant date | Sep 14, 2010 |
| Priority date | — |
| Expiry date | Jun 10, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods of treating a subject having a disease, disorder or condition of the central nervous system. The methods include administering TGF-α polypeptides, related polypeptides, fragments and mimetics thereof useful in stimulating progenitor cell or stem cell proliferation, migration and differentiation. The methods of the invention are useful to treat and prophylactically ameliorate neurological tissue injury in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.