Polymorphic forms of fluvastatin sodium and process for preparing the same

US7795451B2 · kind B2 · utility

Assignee

• Jubilant Organosys Limited · IN

Inventors

• Bhausaheb Chavhan · Hyderabad, IN
• Arun Kumar Awasthi · Savanuru, IN
• Richa Aggarwal · Sidhauli, IN
• Rani S. Beena · Sidhauli, IN
• Soumendu Paul · Noida, IN
• Rajesh Kumar Thaper · Jammu, IN
• Sushil Kumar Dubey · Noida, IN

Key dates

• Filing date: Feb 10, 2006
• Grant date: Sep 14, 2010
• Expiry date: Jul 15, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D209/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed herein are novel polymorphic forms of Fluvastatin sodium, wherein said polymorphic forms are designated as JF, JF1, JF2, JF3 and are characterized by their powder X-ray diffraction patterns, Infrared absorption spectrums, thermo gravimetric analysis and differential scanning calorimetry. The processes for preparing said polymorphic forms are also disclosed. The present invention also relates to process for preparing amorphous form of Fluvastatin sodium.