Patent · US Active

Paricalcitol purification

US7795459B2 · kind B2 · utility

0Cited by

2References

14Claims

0Family size

Assignee

Alphora Research Inc. · CA

Inventors

Fabio Souza · Mississauga, CA
Ming Pan · Mississauga, CA
Kathleen Da Silva Turcot · Toronto, CA

Key dates

Filing date	Apr 28, 2009
Grant date	Sep 14, 2010
Priority date	—
Expiry date	Apr 28, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2602/24
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Paricalcitol, a synthetic vitamin D analog, is purified to a purity greater than 99.7% by crystallization from solution in isopropyl acetate solvent, followed by filtration and vacuum drying. Isopropyl acetate appears to be unique among commonly available and pharmaceutically acceptable solvents in its ability to precipitate paricalcitol in this high purity, essentially free of isomers thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.