Liquid chromatography-mass spectrometry
US7797988B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 21, 2008 |
| Grant date | Sep 21, 2010 |
| Priority date | — |
| Expiry date | Apr 22, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/8447
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A liquid chromatography/mass spectrometry system includes a chromatographic column through which an effluent passes, wherein the effluent comprises a plurality of analytes that correspond to a plurality of chromatographic peaks and an eluent; a post-column splitter having at least two output ports through which the effluent of the column is split to at least a first portion and a second portion; a mass spectrometer configured to receive the first portion from a first of the output ports for analysis; and a tube connected to a second of the output ports configured to prevent substantial evaporation of the eluent in the second portion until undergoing mass spectrometry. The second portion has a plurality of separated analytes corresponding to at least two chromatographic peaks. A method of using the system is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.