Aryl nitrile compounds and compositions and their uses in treating inflammatory and related disorders
US7799795B2 · kind B2 · utility
19Cited by
9References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 26, 2006 |
| Grant date | Sep 21, 2010 |
| Priority date | — |
| Expiry date | Nov 7, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D513/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are compounds of the formulawhere A1, A2, A3, A4, L, Q, R1, R2, R3, R4, Rx, Ry, Rz, X, Y1, Y2, Y4 and Z are as described herein, and compositions thereof that are useful in the treatment of inflammatory and immune conditions and diseases. In particular, the invention provides aryl nitrile compounds which modulate the expression and/or function of a chemokine receptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.