Toxoplasma gondii mutant with enhanced homologous recombination and uses thereof
US7803389B2 · kind B2 · utility
1Cited by
0References
15Claims
0Family size
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Key dates
| Filing date | Feb 27, 2009 |
| Grant date | Sep 28, 2010 |
| Priority date | — |
| Expiry date | Feb 27, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/523
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a mutant Toxoplasma gondii which exhibits enhanced homologous recombination. The mutant of the present invention is a knockout in the KU80-dependent nonhomologous end-joining pathway which finds application in generating T. gondii gene knockouts and gene replacements for use in vaccine and drug development.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.