Antigenic HIV gp41 chimeric polypeptides comprising the MVP5180/91 epitope SKGKLIS

US7803524B2 · kind B2 · utility

Assignee

• Siemens Healthcare Diagnostics Products GmbH · DE

Inventors

• Stefan Brust · Marburg, DE
• Stefan Knapp · Marburg, DE
• Manfred Gerken · Marburg, DE
• Lutz G. Guertler · Munich, DE

Key dates

• Filing date: Mar 21, 2005
• Grant date: Sep 28, 2010
• Expiry date: May 7, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2740/16134
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Immunologically active peptides which are derived from a novel immunodeficiency virus which has the designation MVP5180/91 are described. A diagnostic composition containing such a peptide and methods of detecting an antibody against a retrovirus that causes immune deficiency using such diagnostic composition are also described. A kit containing the immunologically active peptides is also described. An immunogen and method of immunizing a mammal against HIV infection using the immunologically active peptides is described. DNA encoding the peptides and methods of detecting nucleic acids encoding HIV viruses are also described.