Marburg I mutant of factor VII activating protease (FSAP) as risk factor for arterial thrombosis and methods of detecting FSAP and FSAP mutations

US7803569B2 · kind B2 · utility

Assignee

• CSL Behring AG · DE

Inventors

• Stefan Kiechl · Zirl, AT
• Johann Willeit · Innsbruck, AT
• Christian Wiedermann · Innsbruck, AT
• Juergen Roemisch · Marburg, DE
• Thomas Weimer · Gladenbach, DE
• Annette Feussner · Marburg, DE
• Hans-Arnold Stoehr · Wetter, DE
• Volker Doersam · Marburg, DE
• Wiegand Lang · Cölbe, DE
• Margret Becker · Marburg, DE
• Claudia Nerlich · Marburg, DE
• Gudrun Muth-Naumann · Wetter, DE
• Bernd Knoblauch · Lich, DE

Key dates

• Filing date: Dec 5, 2006
• Grant date: Sep 28, 2010
• Expiry date: Aug 4, 2028

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/323
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

An arterial thrombosis risk factor comprising one or more of the identified mutants of coagulation factor VII activating protease (FSAP) is described. In addition, diagnostic determination methods for detecting these mutants which are identified as risk factors are described.