Intravenous delivery of polynucleotides to cells in mammalian limb
US7803782B2 · kind B2 · utility
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30Claims
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Key dates
| Filing date | May 27, 2004 |
| Grant date | Sep 28, 2010 |
| Priority date | — |
| Expiry date | Mar 19, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An intravenous delivery method is described that enables delivery of polynucleotides to extravascular cells of a mammalian limb. The method involves the injection of polynucleotides into a distal vein of a limb that is transiently occluded. Polynucleotide delivery is facilitated by rapid injection in sufficient volume to enable extravasation of the solution into surrounding tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.