Stabilized liquid polypeptide-containing pharmaceutical compositions
US7807142B2 · kind B2 · utility
21Cited by
16References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 5, 2005 |
| Grant date | Oct 5, 2010 |
| Priority date | — |
| Expiry date | Dec 5, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Stabilized liquid polypeptide-containing pharmaceutical compositions are provided. The compositions comprise an amino acid base, which serves as the primary stabilizing agent of the polypeptide, and an acid and/or its salt form to buffer the solution within an acceptable pH range for stability of the polypeptide. Methods for increasing stability of a polypeptide in a liquid pharmaceutical composition and for increasing storage stability of such a pharmaceutical composition are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.